Should Herpes Be Tested by Lesion PCR or by Blood?
Medically reviewed by our MD Laboratory Director (a role required by CLIA; the director's name is on file in the CMS CLIA database, #45D2048957, and can be verified independently) · Editorial policy

Swab the sore. If there is no sore, think hard before ordering a blood test you may misread.CLIA #45D2048957 · CAP #8722734 · Same-day results · Walk-ins welcome
Lesion PCR when a sore is present: it identifies the virus and its type, directly. Type-specific IgG tells you only that you were exposed at some point in your life — not when, not where, and not whether the sore in front of you is herpes. HSV IgM is not recommended by CDC; it is a well-known generator of false positives and unnecessary panic.
Not sure what you need? Text us and we will set it up.
📱 Text (713) 832-8892 📞 Call (713) 266-0808
📱 Text (713) 832-8892 📞 Call (713) 266-0808
3707 Westcenter Dr Suite 100, Houston, TX 77042 · Walk-ins welcome
Matching the test to the question
| Your situation | Right test |
|---|---|
| You have a sore right now | Lesion PCR — come in today, while it is fresh |
| No symptoms, general screening curiosity | Routine serologic screening is not recommended by CDC for the general population |
| Partner has HSV; you want to know your status | Type-specific IgG — discuss interpretation with the physician first |
| Anyone offering you an IgM test | Decline, and ask why |
A positive HSV-1 IgG in an adult is close to meaningless on its own — a large share of the population carries it, mostly from childhood oral exposure.
We name drugs, never doses. Treatment statements follow CDC guidance; the physician decides what you actually take.
Same day, start to finish. Sample by 1:00 PM → results at 4:30 PM → if treatment is clinically appropriate, a licensed physician in our partner network sees you between 4:30 and 6:00 PM, a few minutes away. That window is reserved for patients tested here, and your slot is held the moment we take your sample — the slot is held, not hunted. On your own, a same-day appointment is nearly impossible; at an urgent care, you wait in the queue. STAT: ~2 hours, sample in by 3:00 PM.
FAQ
- My sore is crusting over. Should I still come?
- Yes, today. Sensitivity falls as the lesion heals, and we would rather tell you that up front than run a test that cannot help.
- Can PCR tell HSV-1 from HSV-2?
- Yes, and the distinction matters for counseling.
- Why is IgM bad?
- It cross-reacts and produces false positives, and it does not reliably indicate recent infection. CDC does not recommend it.
- Is there treatment?
- Yes — antiviral therapy suppresses outbreaks and reduces transmission. The physician decides what is appropriate.
Not sure what you need? Text us and we will set it up.
📱 Text (713) 832-8892 📞 Call (713) 266-0808
📱 Text (713) 832-8892 📞 Call (713) 266-0808
3707 Westcenter Dr Suite 100, Houston, TX 77042 · Walk-ins welcome
References
- CDC — STI Treatment Guidelines, 2021
- CDC — Genital Herpes (Detailed)
- Our CLIA #45D2048957 and CAP #8722734 credentials — verify them yourself
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